Searchable abstracts of presentations at key conferences in endocrinology

ea0013p312 | Thyroid | SFEBES2007

Using an increased fixed dose of 131I (600MBq) leads to improved outcome in patients with hyperthyroidism

Boelaert Kristien , Manji Nilusha , Sheppard Michael , Gough Stephen , Franklyn Jayne

We have previously (Allehabadia et al., JCEM, 2001) reported better cure rates for patients treated with a single fixed dose of 370 MBq 131I compared with 185 MBq. We have since increased the standard dose of administered radioiodine to 600 MBq and re-audited our data in 1240 consecutive thyrotoxic patients. We aimed to compare the efficacy of the new dose regimen and to explore factors that might predict outcome. Patients were categorised in 3 diagnostic gro...